KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
24.85
Human Site:
Y214
Identified Species:
42.05
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
Y214
L
W
F
Y
A
K
I
Y
K
A
V
R
Q
H
C
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
Y214
L
W
F
Y
A
K
I
Y
K
A
V
R
Q
H
C
Rhesus Macaque
Macaca mulatta
P56490
532
60122
Y217
T
I
L
Y
C
R
I
Y
R
E
T
E
K
R
T
Dog
Lupus familis
XP_541769
536
61594
Y263
L
W
F
Y
A
R
I
Y
K
A
V
R
Q
H
C
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
Y214
L
W
F
Y
V
K
I
Y
K
A
V
R
R
H
C
Rat
Rattus norvegicus
P31390
486
55674
Y214
L
W
F
Y
V
K
I
Y
K
A
V
R
R
H
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
R214
V
R
R
H
C
Q
H
R
E
L
I
N
G
S
F
Chicken
Gallus gallus
P30372
466
51547
S213
T
V
L
Y
W
Q
I
S
R
A
S
K
S
R
I
Frog
Xenopus laevis
P30544
484
54107
S220
T
I
L
Y
I
H
I
S
L
A
S
R
S
R
V
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
F239
L
V
F
Y
S
Q
I
F
I
A
V
R
D
H
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
R261
W
N
I
F
K
A
L
R
S
R
A
R
K
Q
R
Honey Bee
Apis mellifera
XP_395477
546
60788
G267
V
L
F
I
L
Y
G
G
I
Y
K
T
A
Y
D
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
Y228
L
F
A
Y
G
K
V
Y
I
I
A
T
R
H
S
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
F249
L
F
V
Y
G
K
I
F
Y
E
I
K
T
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
20
93.3
N.A.
86.6
86.6
N.A.
0
20
26.6
53.3
N.A.
6.6
6.6
33.3
26.6
P-Site Similarity:
100
100
40
100
N.A.
93.3
93.3
N.A.
33.3
40
26.6
73.3
N.A.
26.6
20
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
22
8
0
0
0
58
15
0
8
0
0
% A
% Cys:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
36
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
8
15
0
8
0
0
0
% E
% Phe:
0
15
50
8
0
0
0
15
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
15
0
8
8
0
0
0
0
8
0
0
% G
% His:
0
0
0
8
0
8
8
0
0
0
0
0
0
50
0
% H
% Ile:
0
15
8
8
8
0
72
0
22
8
15
0
0
0
8
% I
% Lys:
0
0
0
0
8
43
0
0
36
0
8
15
15
0
0
% K
% Leu:
58
8
22
0
8
0
8
0
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
22
0
0
0
0
0
0
22
8
0
% Q
% Arg:
0
8
8
0
0
15
0
15
15
8
0
58
22
29
8
% R
% Ser:
0
0
0
0
8
0
0
15
8
0
15
0
15
8
15
% S
% Thr:
22
0
0
0
0
0
0
0
0
0
8
15
8
0
8
% T
% Val:
15
15
8
0
15
0
8
0
0
0
43
0
0
0
8
% V
% Trp:
8
36
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
79
0
8
0
50
8
8
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _